I thought about starting fresh with a new SSD in Lion until I realized that I'd need the AppStore to get it. Since I'm a friend of clean installs I wondered if there would be a way around this. So I figured what the hell I'll write Steve Jobs a mail asking him about this matter:
I just wanted to know if there will be a way to install Lion on a new HDD/SSD without previously installing 10.6?
And he really replied in his strung-out manner:
Sent from my iPhone